Structure of D-ribulose 5-phosphate 3-epimerase from Synechocystis to 1.6 A resolution.

نویسندگان

  • Eric L Wise
  • Julie Akana
  • John A Gerlt
  • Ivan Rayment
چکیده

The crystal structure of D-ribulose 5-phosphate 3-epimerase (RPE) from the cyanobacterium Synechocystis was determined by X-ray crystallography to 1.6 A resolution. The enzyme, which catalyzes the epimerization of D-ribulose 5-phosphate and D-xylulose 5-phosphate, assembles as a hexamer of (beta/alpha)(8)-barrels in the crystallographic asymmetric unit. The active site is highly similar to those of two previously reported RPEs and provides further evidence for essential catalytic roles for several active-site residues.

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عنوان ژورنال:
  • Acta crystallographica. Section D, Biological crystallography

دوره 60 Pt 9  شماره 

صفحات  -

تاریخ انتشار 2004